β-endorphin appears to play a definite role in the biologic response to stress and the endogenous mechanism of apin reception. This study was proposed to investigate the effects of upper abdominal surgery on plasma β-endorphin level in 18
persons(Experimental group: 13, Control group: 5) by means of radioimmunoassay using β-endorphin Kit(incstar plasma β-endorphin Kit group: 5) by means of radioimmunoassay using β-endorphin Kit(Incstear plasmaβ-endorphin Kit cast. #46065) and
Automatic Gamma scintillation Counter(Micromedic Systems 4/200).
@ES The results were as follows:
@EN 1) Plasma β-endorphin levels were significantly increased in extubation and two hours after operation, (P<0.01) but, significantly decreased in 24 hours after operation(P<0.05).
2) Plasma β-endorphin levels were significantly increased in extubation(P<0.01), but, thereafter no significant change in control group.
In conclusion, plasma β-endorphin was increased during postoperative pain, which was considered as a response of the stress. The β-endorphin was increased significantly during postoperative two hours and then decreased.
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